Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.

Van Laethem, K; Schmit, J; Pelemans, H; Balzarini, J; Witvrouw, M; Pérez-Pérez, M; Camarasa, M; Esnouf, R; Aquaro, S; Cenci, A; Perno, C; Hermans, P; Sprecher, S; Ruiz, L; Clotet, B; Van Wijngaerden, E; Van Ranst, M; Desmyter, J; De Clercq, E; Vandamme, A

Journal article

Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.

Abstract:: HIV-1 samples from six patients undergoing diverse anti-HIV therapies possessed the E138A mutation in their reverse transcriptase (RT) genome. Patients were receiving the following therapies: TIBO monotherapy (one patient); zidovudine plus didanosine combination therapy (one); zidovudine monotherapy (one); sequential therapy with zidovudine, then stavudine and finally zalcitabine plus didanosine (one); and two were drug naive. E138K, not E138A, is a known TSAO-specific resistance mutation, em...
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APA Style

Van Laethem, K., Schmit, J., Pelemans, H., Balzarini, J., Witvrouw, M., Pérez-Pérez, M., Camarasa, M., Esnouf, R., Aquaro, S., Cenci, A., Perno, C., Hermans, P., Sprecher, S., Ruiz, L., Clotet, B., Van Wijngaerden, E., Van Ranst, M., Desmyter, J., De Clercq, E., & Vandamme, A. (2000). Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients. AIDS Research and Human Retroviruses, 16(9), 825–833.

MLA Style

Van Laethem, K., et al. “Presence of 2',5'-Bis-O-(Tert-Butyldimethylsilyl)-3'-Spiro-5’-(4’-Amino-1’,2’-Oxath Iole-2’,2’-Dioxide) (TSAO)-Resistant Virus Strains in TSAO-Inexperienced HIV Patients.” AIDS Research and Human Retroviruses, vol. 16, no. 9, 2000, pp. 825–33.

Chicago Style

Van Laethem, K, J Schmit, H Pelemans, J Balzarini, M Witvrouw, M Pérez-Pérez, M Camarasa, et al. 2000. “Presence of 2',5'-Bis-O-(Tert-Butyldimethylsilyl)-3'-Spiro-5’-(4’-Amino-1’,2’-Oxath Iole-2’,2’-Dioxide) (TSAO)-Resistant Virus Strains in TSAO-Inexperienced HIV Patients.” AIDS Research and Human Retroviruses 16 (9): 825–33.
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