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Journal article

A phase III, open-label, randomised multicentre study to evaluate the immunogenicity and safety of a booster dose of two different reduced antigen diphtheria-tetanus-acellular pertussis-polio vaccines, when co-administered with measles-mumps-rubella vaccine in 3 and 4-year-old healthy children in the UK

Abstract:

Aim

To evaluate the immunogenicity and safety of a reduced antigen diphtheria-tetanus-acellular pertussis-inactivated poliovirus (dTap-IPVB) vaccine (Boostrix-IPV, GSK) as a pre-school booster in 3–4 year old children as compared to dTap-IPVR (Repevax, Sanofi Pasteur), when co-administered with mumps-measles-rubella vaccine (MMRV).

Methods

This phase III, open label, randomised study was conducted in the UK between April 2011 and April 2012. Children due their pre...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.vaccine.2018.03.021

Authors


Kuriyakose, S More by this author
Mesaros, N More by this author
Tomlinson, R More by this author
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GlaxoSmithKline Biologicals SA More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
23
Issue:
6
Pages:
2300-2306
Publication date:
2018-03-22
Acceptance date:
2018-03-09
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Pubs id:
pubs:832154
URN:
uri:b0c12fba-cf7e-446f-8d99-068a361c073c
UUID:
uuid:b0c12fba-cf7e-446f-8d99-068a361c073c
Local pid:
pubs:832154
Language:
English
Keywords:

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