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Journal article

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection.

Abstract:

Human immunodeficiency virus type 1 (HIV-1) infection of dendritic cells (DCs) has been documented in vivo and may be an important contributor to HIV-1 transmission and pathogenesis. HIV-1-specific CD4(+) T cells respond to HIV antigens presented by HIV-1-infected DCs and in this process become infected, thereby providing a mechanism through which HIV-1-specific CD4(+) T cells could become preferentially infected in vivo. HIV-2 disease is attenuated with respect to HIV-1 disease, and host imm...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.00976-07

Authors


Duvall, MG More by this author
Ambrozak, DA More by this author
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Journal:
Journal of virology
Volume:
81
Issue:
24
Pages:
13486-13498
Publication date:
2007-12-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:b0bd7668-78e5-4e98-af3c-d5974caae08b
Source identifiers:
6062
Local pid:
pubs:6062

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