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Historical review: Cytokines as therapeutics and targets of therapeutics.

Abstract:

Cytokine research has spawned the introduction of new therapies that have revolutionized the treatment of many important diseases. These therapeutic advances have resulted from two very different strategies. The first therapeutic strategy embodies the administration of purified, recombinant cytokines. The second relies on the administration of therapeutics that inhibit the harmful effects of upregulated, endogenous cytokines. Examples of successful cytokine therapeutics include hematopoietic ...

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Publication status:
Published

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Publisher copy:
10.1016/j.tips.2004.02.011

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Trends in pharmacological sciences
Volume:
25
Issue:
4
Pages:
201-209
Publication date:
2004-04-05
DOI:
EISSN:
1873-3735
ISSN:
0165-6147
URN:
uuid:b0902975-49e5-4db5-88dc-5e16c0fdcd59
Source identifiers:
224249
Local pid:
pubs:224249

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