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Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya

Abstract:

Background: Rotavirus, predominantly of group A, is a major cause of severe diarrhoea worldwide, with the greatest burden falling on young children living in less-developed countries. Vaccines directed against this virus have shown promise in recent trials, and are undergoing effectiveness evaluation in sub-Saharan Africa. In this region limited childhood data are available on the incidence and clinical characteristics of severe group A rotavirus disease. Advocacy for vaccine intervention and...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pmed.0050153

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Institution:
"Kenya Medical Research Institute (KEMRI), Centre for Geographic Medicine Research-Coast, Kilifi, Kenya", "University of Warwick"
Department:
Department of Biological Sciences
Role:
Author
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Institution:
"Kenya Medical Research Institute (KEMRI), Centre for Geographic Medicine Research-Coast, Kilifi, Kenya"
Role:
Author
More by this author
Institution:
"Kenya Medical Research Institute (KEMRI), Centre for Geographic Medicine Research-Coast, Kilifi, Kenya"
Role:
Author
More by this author
Institution:
"University of Limpopo, Medunsa Campus, Pretoria, Gauteng, South Africa"
Department:
Medical Research Council (MRC) Diarrhoeal Pathogens Research Unit
Role:
Author
More by this author
Institution:
"University of Limpopo, Medunsa Campus, Pretoria, Gauteng, South Africa"
Department:
Medical Research Council (MRC) Diarrhoeal Pathogens Research Unit
Role:
Author
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Wellcome Trust More from this funder
Kenya Medical Research Institute More from this funder
MRC Diarrhoeal Pathogens Research Unit, South Africa More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
5
Issue:
7
Pages:
Article: e153
Publication date:
2008-07-05
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
URN:
uuid:b0835d6d-9d6e-49e8-a1c6-6cc449d8b0ab
Local pid:
ora:3076

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