Journal article
Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia
- Abstract:
-
Intracytoplasmic aggregation of α-synuclein protein as Lewy bodies in the brainstem neurons is diagnostic for Parkinson's disease, whereas if this process also occurs in the cortical neurons, it is considered pathognomonic for dementia with Lewy bodies. However, the link between α-synuclein incorporation into inclusions, neuronal dysfunction, and clinical symptoms needs to be clarified. Another important issue of the pathogenetic puzzle is to understand where α-synuclein pathology begins and ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1002/ana.20321
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Authors
Funding
Finnish Alzheimer Association
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Kuopio University Hosptial
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Finnish Research Foundation of Orion Corporation
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Finnish Parkinson Association
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Annals of Neurology Journal website
- Volume:
- 57
- Issue:
- 1
- Pages:
- 82-91
- Publication date:
- 2004-11-23
- Acceptance date:
- 2004-09-18
- DOI:
- EISSN:
-
1531-8249
- ISSN:
-
0364-5134
- Source identifiers:
-
579215
Item Description
- Pubs id:
-
pubs:579215
- UUID:
-
uuid:b06272c5-21cd-4d1d-9574-208500b8956f
- Local pid:
- pubs:579215
- Deposit date:
- 2015-12-09
Terms of use
- Copyright holder:
- American Neurological Association
- Copyright date:
- 2004
- Notes:
- © 2005 American Neurological Association. Published by Wiley-Liss, Inc., through Wiley Subscription Services
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