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Journal article

Junctions on the road to cancer.

Abstract:
Mus81-Eme1 is a structure-specific DNA endonuclease complex that processes DNA junctions during the recombinational repair of DNA damage. The recent observation that mice containing disruptions in one or both copies of the MUS81 gene are profoundly cancer prone demonstrates that efficient processing of recombination intermediates is necessary to guard against tumorigenesis.
Publication status:
Published

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Publisher copy:
10.1038/nsmb0804-693

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
Nature structural and molecular biology
Volume:
11
Issue:
8
Pages:
693-695
Publication date:
2004-08-05
DOI:
EISSN:
1545-9985
ISSN:
1545-9993
URN:
uuid:b04b46bf-2856-43cf-b12c-5896bb5c98d6
Source identifiers:
100004
Local pid:
pubs:100004

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