Journal article icon

Journal article

Mutation analysis of glial cell line-derived neurotrophic factor (GDNF), a ligand for the RET/GDNF receptor alpha complex, in sporadic phaeochromocytomas.

Abstract:

Phaeochromocytomas usually occur sporadically but may also be a feature of three autosomal dominantly inherited cancer syndromes, multiple endocrine neoplasia type 2, von Hippel-Lindau disease (VHL), and, very rarely, type 1 neurofibromatosis. Germ-line missense mutations in the RET proto-oncogene, which encodes a receptor tyrosine kinase, cause multiple endocrine neoplasia type 2. In VHL, germ-line mutations in one of the three exons of the VHL tumor suppressor gene have been found in the ma...

Expand abstract
Publication status:
Published

Actions


Authors


Toledo, SP More by this author
Mulligan, LM More by this author
Grossman, AB More by this author
Expand authors...
Journal:
Cancer research
Volume:
57
Issue:
2
Pages:
310-313
Publication date:
1997-01-05
EISSN:
1538-7445
ISSN:
0008-5472
URN:
uuid:b04b3374-0985-4c34-bca7-0b2c3a3c3988
Source identifiers:
138733
Local pid:
pubs:138733

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP