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Journal article

Coffee and tea consumption, genotype-based CYP1A2 and NAT2 activity and colorectal cancer risk-results from the EPIC cohort study.

Abstract:

Coffee and tea contain numerous antimutagenic and antioxidant components and high levels of caffeine that may protect against colorectal cancer (CRC). We investigated the association between coffee and tea consumption and CRC risk and studied potential effect modification by CYP1A2 and NAT2 genotypes, enzymes involved in the metabolization of caffeine. Data from 477,071 participants (70.2% female) of the European Investigation into Cancer and Nutrition (EPIC) cohort study were analyzed. At ba...

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Publication status:
Published

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Publisher copy:
10.1002/ijc.28655

Authors


Bueno-de-Mesquita, HB More by this author
Van Oijen, MG More by this author
Siersema, PD More by this author
Uiterwaal, CS More by this author
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Journal:
International journal of cancer. Journal international du cancer
Volume:
135
Issue:
2
Pages:
401-412
Publication date:
2014-07-05
DOI:
EISSN:
1097-0215
ISSN:
0020-7136
URN:
uuid:b02836de-825f-4c3a-8740-54b0017bf9d0
Source identifiers:
445073
Local pid:
pubs:445073

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