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Tetrazoles of manno- and rhamno-furanoses

Abstract:
The synthesis of tetrazoles derived from D-mannofuranose and both enantiomers of rhamnofuranose provides the first examples of tetrazole analogues of carbohydrates in the furanose form. The D-furanotetrazoles are potential mannosidase inhibitors whereas the L-rhamnotetrazole may interfere with the biosynthesis of cell walls of mycobacteria and provide a strategy for the treatment of tuberculosis and leprosy. © 1995.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON
Volume:
55
Issue:
14
Pages:
4501-4520
Publication date:
1999-04-02
DOI:
ISSN:
0040-4020
URN:
uuid:b019ea9e-9459-400e-899b-d98ec465b1ad
Source identifiers:
36921
Local pid:
pubs:36921
Language:
English

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