- Abstract:
-
Immunological memory is a key characteristic of specific immune responses. Persistence of increased levels of precursor T cells is antigen-independent and is often used as an indicator of T cell memory. This study documents that, depending on the chosen readout, cytotoxic T lymphocyte (CTL) memory against lymphocytic choriomeningitis virus (LCMV) appears long- or short-lived in the absence of persisting antigen. To study T cell memory in the absence of persisting antigen, either short-lived a...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1073/pnas.94.2.640
-
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- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 94
- Issue:
- 2
- Pages:
- 640-645
- Publication date:
- 1997-01-05
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- URN:
-
uuid:b0197579-d46c-47ae-b92f-5a9137fbf25e
- Source identifiers:
-
469169
- Local pid:
- pubs:469169
- Language:
- English
- Keywords:
- Copyright date:
- 1997
Journal article
Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?
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