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Journal article

Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in Mycobacterium tuberculosis-infected individuals.

Abstract:

RATIONALE: An effective new tuberculosis (TB) vaccine regimen must be safe in individuals with latent TB infection (LTBI) and is a priority for global health care. OBJECTIVES: To evaluate the safety and immunogenicity of a leading new TB vaccine, recombinant Modified Vaccinia Ankara expressing Antigen 85A (MVA85A) in individuals with LTBI. METHODS: An open-label, phase I trial of MVA85A was performed in 12 subjects with LTBI recruited from TB contact clinics in Oxford and London or by poster...

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Publication status:
Published

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Publisher copy:
10.1164/rccm.200809-1486oc

Authors


Sander, CR More by this author
Pathan, AA More by this author
Beveridge, NE More by this author
Poulton, I More by this author
Minassian, A More by this author
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Journal:
American journal of respiratory and critical care medicine
Volume:
179
Issue:
8
Pages:
724-733
Publication date:
2009-04-05
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:b00836b3-70dc-4e17-8beb-fbda1789215a
Source identifiers:
13467
Local pid:
pubs:13467

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