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Counting all possible ancestral configurations of sample sequences in population genetics.

Abstract:

Given a set D of input sequences, a genealogy for D can be constructed backward in time using such evolutionary events as mutation, coalescent, and recombination. An ancestral configuration (AC) can be regarded as the multiset of all sequences present at a particular point in time in a possible genealogy for D. The complexity of computing the likelihood of observing D depends heavily on the total number of distinct ACs of D and, therefore, it is of interest to estimate that number. For D cons...

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Publication status:
Published

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Publisher copy:
10.1109/tcbb.2006.31

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Journal:
IEEE/ACM transactions on computational biology and bioinformatics / IEEE, ACM
Volume:
3
Issue:
3
Pages:
239-251
Publication date:
2006-07-05
DOI:
EISSN:
1557-9964
ISSN:
1545-5963
URN:
uuid:afe16569-f357-494b-86f6-3d1beb46f9ad
Source identifiers:
102866
Local pid:
pubs:102866

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