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Journal article

Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition.

Abstract:

Western style diets and lifestyles are associated with increasing rates of obesity, diabetes and insulin resistance. Higher circulating insulin levels may modulate cell proliferation and apoptosis either directly or indirectly by increasing the bioactivity of IGF-I and decreasing the bioactivity of some of its binding proteins. The objective of this study was to determine the association of increasing levels of serum C-peptide, a biomarker of pancreatic insulin secretion, and IGF binding prot...

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Publication status:
Published

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Publisher copy:
10.1002/ijc.22697

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Journal:
International journal of cancer. Journal international du cancer
Volume:
121
Issue:
2
Pages:
368-376
Publication date:
2007-07-05
DOI:
EISSN:
1097-0215
ISSN:
0020-7136
URN:
uuid:afae3d2d-5c5c-4ff4-a80d-9c99fe4fa9f3
Source identifiers:
23027
Local pid:
pubs:23027

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