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Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation (Review)

Abstract:

Background Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, some areas continue to provoke debate, especially concerning the use of prophylactic platelet transfusions for the prevention of thrombocytopenic bleeding. This is an update of a Cochrane review first published in 2004, and previous...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
Stanworth, SJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, CSM
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
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Publisher:
John Wiley and Sons, Ltd Publisher's website
Journal:
Cochrane Database of Systematic Reviews Journal website
Volume:
2015
Issue:
11
Publication date:
2015-11-05
DOI:
ISSN:
1469-493X
URN:
uuid:afa3d902-a3dc-4866-a153-2c576ff7a9cd
Source identifiers:
574500
Local pid:
pubs:574500

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