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Common predisposition alleles for moderately common cancers: bladder cancer.

Abstract:

Bladder cancer is the 5th commonest cancer and two major risk factors are smoking and occupational chemical exposure. There is also evidence of a genetic component to its aetiology. Candidate gene studies have mostly focused on genes involved in adduct metabolism and DNA repair, including a recent consortium-based meta-analysis. Recently, two genome-wide association studies in bladder cancer have been published and a third is awaited with interest. These first two studies have identified thre...

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Publication status:
Published

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Publisher copy:
10.1016/j.gde.2010.01.002

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Journal:
Current opinion in genetics and development
Volume:
20
Issue:
3
Pages:
218-224
Publication date:
2010-06-05
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
URN:
uuid:afa05b45-3bde-4ef2-ad79-527a3bed8963
Source identifiers:
131051
Local pid:
pubs:131051

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