- Abstract:
-
Following anti-malarial drug treatment asexual malaria parasite killing and clearance appear to be first order processes. Damaged malaria parasites in circulating erythrocytes are removed from the circulation mainly by the spleen. Splenic clearance functions increase markedly in acute malaria. Either the entire infected erythrocytes are removed because of their reduced deformability or increased antibody binding or, for the artemisinins which act on young ring stage parasites, splenic pitting...
Expand abstract - Publication status:
- Published
- Peer review status:
- Reviewed (Other)
- Version:
- Publisher's version
- Files:
-
-
(pdf, 633.6KB)
-
(pdf, 2.1MB)
-
- Publisher copy:
- 10.1186/s12936-017-1731-1
-
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- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria Journal Journal website
- Volume:
- 16
- Issue:
- 1
- Pages:
- Article: 88
- Publication date:
- 2017-02-05
- Acceptance date:
- 2017-02-08
- DOI:
- ISSN:
-
1475-2875
- Pubs id:
-
pubs:678927
- URN:
-
uri:af83f768-7199-4572-84f6-b7f77cb6f7ee
- UUID:
-
uuid:af83f768-7199-4572-84f6-b7f77cb6f7ee
- Local pid:
- pubs:678927
- Paper number:
- 1
- Copyright holder:
- Nicholas J. White
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 The Authors. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. ERRATUM published 2017-05-10 at (Malaria Journal: 2017 16:194 doi.org/10.1186/s12936-017-1785-0).
Journal article
Malaria parasite clearance
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