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Determination of oxygen relaxivity in oxygen nanobubbles at 3 and 7 Tesla

Abstract:

Objective Oxygen-loaded nanobubbles have shown potential for reducing tumour hypoxia and improving treatment outcomes, however, it remains difficult to noninvasively measure the changes in partial pressure of oxygen (PO2) in vivo. The linear relationship between PO2 and longitudinal relaxation rate (R1) has been used to noninvasively infer PO2 in vitreous and cerebrospinal fluid, and therefore, this experiment aimed to investigate whether R1 is a suitable measurement to study oxygen delivery ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s10334-022-01009-3

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Role:
Author
ORCID:
0000-0001-5970-9100
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Role:
Author
ORCID:
0000-0003-0720-421X
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Name:
Engineering and Physical Sciences Research Council
Publisher:
Springer
Journal:
Magnetic Resonance Materials in Physics, Biology and Medicine More from this journal
Volume:
35
Issue:
5
Pages:
817-826
Publication date:
2022-04-13
Acceptance date:
2022-03-18
DOI:
EISSN:
1352-8661
ISSN:
0968-5243
Pmid:
35416627
Language:
English
Keywords:
Pubs id:
1250718
Local pid:
pubs:1250718
Deposit date:
2022-11-04

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