Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.

Journal article

We investigated the outcome for children and young people with Early T-precursor acute lymphoblastic leukaemia (ETP-ALL), a recently described poor prognosis sub-group of T-ALL, treated on a contemporary protocol, UKALL 2003. After a median follow-up of 4 years and 10 months, the ETP sub-group, representing 16% of T-ALL patients, had non-significantly inferior 5-year event-free survival (76·7% vs. 84·6%, P = 0·2) and overall survival (82·4% vs. 90·9%, P = 0·1), and a higher relapse rate (18·6...

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Authors: Patrick, K; Wade, R; Goulden, N; Mitchell, C; Moorman, A

• Publication status: Published
• Journal: British journal of haematology
• Volume: 166
• Issue: 3
• Pages: 421-424
• Publication date: 2014-08-01
• DOI: 10.1111/bjh.12882
• EISSN: 1365-2141
• ISSN: 0007-1048
• Language: English
• Keywords: Neoplasm Staging; Antineoplastic Combined Chemotherapy Protocols; Child; Young Adult; Child, Preschool; Humans; Adult; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Male; Female; Treatment Outcome; Infant; Adolescent