Journal article
Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis.
- Abstract:
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Vasoactive intestinal peptide (VIP) is an anti-inflammatory immunomodulatory neuropeptide with therapeutic potential demonstrated for collagen-induced arthritis. The aim of this study was to characterise its potential anti-arthritic effect on human monocytes, macrophages, T cells, and rheumatoid arthritis synovial membrane cells. Monocytes, macrophages, and T cells derived from human peripheral blood were treated with VIP and compared with other cAMP-elevating drugs for a range of activating ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 447.7KB, Terms of use)
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- Publisher copy:
- 10.1186/ar999
Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- Arthritis research and therapy More from this journal
- Volume:
- 5
- Issue:
- 6
- Pages:
- R317-R328
- Publication date:
- 2003-01-01
- DOI:
- EISSN:
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1478-6362
- ISSN:
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1478-6354
Item Description
- Language:
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English
- Keywords:
-
- UUID:
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uuid:af3ef70c-d506-4130-b6e5-16efcb7d6a6a
- Local pid:
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pubs:224119
- Source identifiers:
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224119
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Foey et al
- Copyright date:
- 2003
- Notes:
- © 2003 Foey et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. The electronic version of this article is the complete one and can be found online at: http://arthritis-research.com/content/5/6/R317
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