Journal article icon

Journal article

Partial reduction of pyridinium salts as a versatile route to dihydropyridones.

Abstract:
[reaction: see text] The addition of two electrons to a pyridinium salt turns it into a nucleophile. The intermediate generated by the reduction of such salts can be reacted successfully with a range of different electrophiles (acids, alkyl halides, and carbonyl compounds) and the intermediate hydrolyzed in situ to provide a wide range of dihydropyridones. Each position on the dihydropyridone ring is then accessible using standard synthetic manipulations.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/ol0476624

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Johnson, DJ More by this author
Bamford, MJ More by this author
Ichihara, O More by this author
Journal:
Organic letters
Volume:
7
Issue:
3
Pages:
435-437
Publication date:
2005-02-05
DOI:
EISSN:
1523-7052
ISSN:
1523-7060
URN:
uuid:af26c316-9bb6-455b-b03f-16506919b03c
Source identifiers:
32970
Local pid:
pubs:32970

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP