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Angiogenesis in joint disease: The need for clinical data

Abstract:

Rheumatoid arthritis (RA) is a widely studied inflammatory joint disease which impacts hugely on patients quality of life. The challenge remains to improve on current treatments, such as TNF inhibitors, which despite their unquestionable clinical success, are associated with increased infection risk and are not effective in all patients. There are certain similarities between RA and solid tumors, such as the presence of inflammatory cells and cytokines, hypoxia, invasiveness and excessive cel...

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Publisher copy:
10.2217/ijr.10.41

Authors


Paleolog, EM More by this author
Journal:
International Journal of Clinical Rheumatology
Volume:
5
Issue:
4
Pages:
439-449
Publication date:
2010-08-05
DOI:
ISSN:
1758-4272
URN:
uuid:aeffa3f1-4a6d-40c6-821e-44934ca84240
Source identifiers:
232203
Local pid:
pubs:232203
Language:
English
Keywords:

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