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Journal article

Determining the relationship between blood pressure, kidney function, and chronic kidney disease: insights from genetic epidemiology

Abstract:

Background:

It is well established that decreased kidney function can increase blood pressure (BP), but it is unproven whether moderately elevated BP causes chronic kidney disease (CKD) or glomerular hyperfiltration.

Methods:

Three hundred eleven thousand one hundred nineteen White British UK Biobank participants were included in logistic regression analyses to estimate the odds of CKD (defined as long-term kidney replacement therapy, estimated... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/HYPERTENSIONAHA.122.19354

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0003-1172-8243
Publisher:
American Heart Association
Journal:
Hypertension More from this journal
Volume:
79
Issue:
12
Pages:
2671-2681
Publication date:
2022-09-09
Acceptance date:
2022-08-17
DOI:
EISSN:
1524-4563
ISSN:
0194-911X
Language:
English
Keywords:
Pubs id:
1274494
Local pid:
pubs:1274494
Deposit date:
2022-08-19

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