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Thesis

Neuroprotection of cone photoreceptors in retinitis pigmentosa

Abstract:

Retinitis pigmentosa (RP) is a genetically and phenotypically heterogeneous condition that affects approximately 1 in 4000 individuals worldwide. The most common presentation of RP is a rod-cone dystrophy, where the degeneration of cone photoreceptors occurs secondary to advanced rod loss, leading to a significant decline in central vision and a corresponding reduction in patient quality of life. The mechanisms underlying secondary cone loss are poorly understood, particularly in disorders...

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Institution:
University of Oxford
Oxford college:
Merton College
Department:
Medical Sciences Division - Ophthalmology
Role:
Author

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Supervisor
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Funding agency for:
Daniel Mark Lipinski
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:aee440bc-f990-4216-9d43-63902ff0fc52
Local pid:
ora:7253

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