Journal article
A humanized mouse model of HPV-associated pathology driven by E7 expression
- Abstract:
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Human papillomavirus (HPV) is the causative agent of human cervical cancer and has been associated with oropharyngeal squamous cell carcinoma development. Although prophylactic vaccines have been developed, there is a need to develop new targeted therapies for individuals affected with malignant infected lesions in these locations, which must be tested in appropriate models. Cutaneous beta HPV types appear to be involved in skin carcinogenesis. Virus oncogenicity is partly achieved by inactiv...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.7MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0041743
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS ONE More from this journal
- Volume:
- 7
- Issue:
- 7
- Pages:
- e41743
- Publication date:
- 2012-07-23
- Acceptance date:
- 2012-06-27
- DOI:
- EISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
-
- UUID:
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uuid:aedbdeb2-1a4d-4a04-9da6-c6fa7fd5701c
- Local pid:
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pubs:344693
- Source identifiers:
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344693
- Deposit date:
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2013-11-16
Terms of use
- Copyright holder:
- Buitrago-Perez et al
- Copyright date:
- 2012
- Notes:
- © 2012 Buitrago-Perez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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