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Synthesis of fluorophore and quencher monomers for use in scorpion primers and nucleic acid structural probes.

Abstract:
We report the syntheses of monomers to incorporate fluorescein and methyl red within the sequence and at the termini of modified oligonucleotides. These monomers have been used in the solid-phase synthesis of fluorogenic oligonucleotides for genetic analysis and the study of multi-stranded nucleic acid structures.
Publication status:
Published

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Publisher copy:
10.1039/b301859h

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
Organic and biomolecular chemistry
Volume:
1
Issue:
13
Pages:
2267-2275
Publication date:
2003-07-05
DOI:
EISSN:
1477-0539
ISSN:
1477-0520
URN:
uuid:aec94916-8e4d-4430-bf66-43c30ef9c61c
Source identifiers:
400055
Local pid:
pubs:400055

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