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Cerebellar GABA change during visuomotor adaptation relates to adaptation performance and cerebellar network connectivity: a magnetic resonance spectroscopic imaging study

Abstract:

Motor adaptation is crucial for performing accurate movements in a changing environment and relies on the cerebellum. Although cerebellar involvement has been well characterized, the neurochemical changes in the cerebellum underpinning human motor adaptation remain unknown. We used a novel magnetic resonance spectroscopic imaging (MRSI) technique to measure changes in the inhibitory neurotransmitter GABA in the human cerebellum during visuomotor adaptation. Participants (n ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1523/jneurosci.0096-22.2022

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-7159-7025
More by this author
Role:
Author
ORCID:
0000-0001-5376-0431
More by this author
Role:
Author
ORCID:
0000-0003-4757-1655
Publisher:
Society for Neuroscience
Journal:
Journal of Neuroscience More from this journal
Volume:
42
Issue:
41
Pages:
7721-7732
Place of publication:
United States
Publication date:
2022-09-09
Acceptance date:
2022-06-16
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Pmid:
36414012
Language:
English
Keywords:
Pubs id:
1299648
Local pid:
pubs:1299648
Deposit date:
2023-03-09

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