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Cotrimoxazole treats fluoroquinolone-resistant Salmonella typhi H58 infection

Abstract:

A woman aged 20 years presented with fever and no localising signs. She was treated with cotrimoxazole and the subsequent blood culture was positive for Salmonella typhi (S. typhi), which was resistant to fluoroquinolones but susceptible to cotrimoxazole. Genotyping identified an FQ-R subclade of H58 S. typhi Fever clearance time was 4 days after starting the antibiotics, and no relapses were noted on 2 months of follow-up. This inexpensive, well-known and easily available antimicrobial could...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1136/bcr-2016-217223

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Department:
Oxford, MSD, NDM, Tropical Medicine
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Department:
Oxford, MSD, NDM, Tropical Medicine
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Case Reports Journal website
Volume:
2016
Pages:
Article: bcr2016217223
Publication date:
2016-10-26
Acceptance date:
2016-10-14
DOI:
ISSN:
1757-790X
Pubs id:
pubs:656959
URN:
uri:ae821dc5-9bcd-4898-a121-d9f2a241e51c
UUID:
uuid:ae821dc5-9bcd-4898-a121-d9f2a241e51c
Local pid:
pubs:656959
Language:
English
Keywords:

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