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Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Abstract:

Lipoprotein(a) concentrations in plasma are associated with cardiovascular risk in the general population. Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in patients with established coronary heart disease remains less clear.We obtained data from 3313 patients with established coronary heart disease in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. We tested associations of tertiles of lipoprotein(a) concentration in plasma and two LP...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1016/s2213-8587(17)30096-7

Authors


Zewinger, S More by this author
Kleber, ME More by this author
Tragante, V More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Publisher:
Elsevier Publisher's website
Journal:
Lancet Diabetes & Endocrinology Journal website
Volume:
5
Issue:
7
Pages:
534-543
Publication date:
2017-05-26
Acceptance date:
2017-02-14
DOI:
EISSN:
2213-8595
ISSN:
2213-8587
Pubs id:
pubs:698807
URN:
uri:ae48f47e-2213-4d4c-8bbb-5142271449db
UUID:
uuid:ae48f47e-2213-4d4c-8bbb-5142271449db
Local pid:
pubs:698807
Language:
English
Keywords:

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