Journal article
5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon.
- Abstract:
-
Gamma interferon (IFN gamma) impairs epithelial barrier function and induces HLA-DR expression on colonic cancer cell lines. Salicylates have been shown to reduce IFN gamma induced HLA-DR expression. The effect of 5-aminosalicylic acid (5-ASA) on IFN gamma induced changes in transepithelial resistance and permeability was investigated in HT29 clone 19A and Caco 2 monolayers. Monolayers were incubated with different concentrations of IFN gamma (100, 500, 1000, and 3000 U/ml) and 5-ASA. IFN gam...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Gut More from this journal
- Volume:
- 38
- Issue:
- 1
- Pages:
- 115-119
- Publication date:
- 1996-01-01
- DOI:
- EISSN:
-
1468-3288
- ISSN:
-
0017-5749
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:135429
- UUID:
-
uuid:ae4035bb-91e8-49ee-911a-a04d2b9b43e0
- Local pid:
-
pubs:135429
- Source identifiers:
-
135429
- Deposit date:
-
2012-12-19
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- Copyright date:
- 1996
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