- Abstract:
-
The maintenance of genome integrity is essential for the regulation of cell proliferation and differentiation. DNA must be accurately duplicated and segregated to daughter cells at cell division, a process that is primarily regulated by cyclin-dependent kinases (CDKs). During cell growth, however, it is inevitable that DNA breaks will occur due to endogenous and exogenous stresses. Interestingly, there is increasing evidence that the catalytic activities of CDKs play critical roles in the DNA...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.dnarep.2008.09.002
-
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- Journal:
- DNA repair
- Volume:
- 8
- Issue:
- 1
- Pages:
- 6-18
- Publication date:
- 2009-01-05
- DOI:
- EISSN:
-
1568-7856
- ISSN:
-
1568-7864
- URN:
-
uuid:ae14de76-fe8e-43a5-b9ae-c02d9c1e1422
- Source identifiers:
-
55362
- Local pid:
- pubs:55362
- Copyright date:
- 2009
Journal article
Dual role of CDKs in DNA repair: to be, or not to be.
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