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Neurochemistry of major depression: a study using magnetic resonance spectroscopy.

Abstract:

RATIONALE: Magnetic resonance spectroscopy (MRS) is an acceptable non-invasive means of studying brain neurochemistry in depression. Previous studies in depressed patients have focused on measurement of the amino acid neurotransmitters, γ-aminobutyric acid (GABA) and glutamate. OBJECTIVES: The aim of this study is to use MRS in conjunction with the ultrashort echo time 'SPECIAL' technique to measure cortical levels of GABA, glutamate and glutathione (GSH) levels in unmedicated patients with m...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-014-3687-y

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Journal:
Psychopharmacology More from this journal
Volume:
232
Issue:
3
Pages:
501-507
Publication date:
2015-02-01
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
Language:
English
Keywords:
Pubs id:
pubs:478355
UUID:
uuid:ade23d64-f267-4c4c-8a95-e9064a3f8585
Local pid:
pubs:478355
Source identifiers:
478355
Deposit date:
2014-09-14

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