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Reference maps of mouse serum acute-phase proteins: changes with LPS-induced inflammation and apolipoprotein A-I and A-II transgenes.

Abstract:

We present reference maps of the mouse serum proteome (run under reducing and non-reducing conditions), from control animals, from mice injected with lipopolysaccharide (LPS) to induce systemic inflammation, and from mice transgenic for human apolipoproteins A-I and A-II. Seventy-seven spots/spot chains from the reducing gels were identified by HPLC MS/MS, representing 28 distinct proteins, including a species-specific protease inhibitor, contrapsin, and high levels of carboxylesterase. The c...

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Publication status:
Published

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Publisher copy:
10.1002/pmic.200401292

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Parolini, C More by this author
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Journal:
Proteomics
Volume:
5
Issue:
16
Pages:
4245-4253
Publication date:
2005-11-05
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
URN:
uuid:adb20c3e-d55f-4a50-8d27-36f394db0cd5
Source identifiers:
230062
Local pid:
pubs:230062

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