Journal article icon

Journal article

The impact of NOD2 variants on fecal microbiota in Crohn's Disease and controls without gastrointestinal disease

Abstract:
Background/Aims Current models of Crohn’s disease (CD) describe an inappropriate immune response to gut microbiota in genetically susceptible individuals. NOD2 variants are strongly associated with development of CD, and NOD2 is part of the innate immune response to bacteria. This study aimed to identify differences in fecal microbiota in CD patients and non-IBD controls stratified by NOD2 genotype. Methods Patients with CD and non-IBD controls of known NOD2... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/ibd/izx061

Authors


More by this author
Role:
Author
ORCID:
0000-0003-4368-1961
More by this author
Role:
Author
ORCID:
0000-0001-5099-8495
More from this funder
Name:
Crohn's and Colitis UK
Grant:
M14-5
More from this funder
Name:
Department of Health
Grant:
CL-2014-01-005
More from this funder
Name:
Medical Research Council
Grant:
MR/M00533X/1
Publisher:
Oxford University Press
Journal:
Inflammatory Bowel Diseases More from this journal
Volume:
24
Issue:
3
Pages:
583–592
Publication date:
2018-02-16
Acceptance date:
2018-02-15
DOI:
EISSN:
1536-4844
ISSN:
1078-0998
Pmid:
29462388
Language:
English
Keywords:
Pubs id:
pubs:911977
UUID:
uuid:adae8748-92d1-4cce-9eeb-2575c00eb581
Local pid:
pubs:911977
Source identifiers:
911977
Deposit date:
2018-09-06

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP