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Lidocaine cytotoxicity to the zygapophysial joints in rabbits: changes in cell viability and proteoglycan metabolism in vitro.

Abstract:

STUDY DESIGN.: To examine whether lidocaine cytotoxicity to chondrocytes has been implicated in the development of osteoarthritis of the zygapophysial joints. OBJECTIVE.: This study was performed to determine the effects of varying concentrations and exposure times of lidocaine on the viability and proteoglycan metabolism of rabbit zygapophysial chondrocytes in vitro. SUMMARY OF BACKGROUND DATA.: Zygapophysial joint injections are commonly administered with lidocaine for chronic spinal pain i...

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Publication status:
Published

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Journal:
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Volume:
34
Issue:
26
Pages:
E945-E951
Publication date:
2009-12-01
DOI:
EISSN:
1528-1159
ISSN:
0362-2436
Language:
English
Keywords:
Pubs id:
pubs:433390
UUID:
uuid:ada8cc71-7dcd-4cda-b5da-dfc6e89b4758
Local pid:
pubs:433390
Source identifiers:
433390
Deposit date:
2013-11-16

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