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Is stress response a new link between adipose tissue and atherogenesis? The role of HSPs/HSF1.

Abstract:

The role of lipids in atherogenesis is well established; sub-endothelial deposition of oxidised low density lipoprotein (ox-LDL) initiates atherosclerotic plaque formation. Circulating cholesterol is regulated by its dietary intake and endogenous synthesis on one hand, and its elimination from the circulation via LDL-receptors/excretion in the bile on the other hand.2 Various lipid-lowering therapies targeting these regulatory mechanisms are used in patients with dyslipidaemias, significant i...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1093/cvr/cvw099

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
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Grant:
FS/16/15/32047 and PG/13/56/30383
Publisher:
Oxford University Press Publisher's website
Journal:
Cardiovascular Research Journal website
Volume:
111
Issue:
1
Pages:
10-12
Publication date:
2016-05-23
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
URN:
uuid:ada6af48-61b7-4753-ab31-9206045479c6
Source identifiers:
625139
Local pid:
pubs:625139
Language:
English

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