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Porphyrins for probing electrical potential across lipid bilayer membranes by second harmonic generation.

Abstract:
Feeling the field! The intensity of second harmonic generation (SHG) from a porphyrin in a lipid bilayer is exceptionally sensitive to electric field, thus indicating that these dyes may be useful probes for electrical signals in excitable cells such as neurons. The porphyrin-based membrane probe (see picture, not to scale) gives a fast electro-optic response which is about 5-10 times greater than those of conventional styryl dyes. Copyright © 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
Publication status:
Published

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Publisher copy:
10.1002/anie.201304515

Authors


Corbett, AD More by this author
Boczarow, I More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Physical and Theoretical Chem
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Journal:
Angewandte Chemie (International ed. in English)
Volume:
52
Issue:
34
Pages:
9044-9048
Publication date:
2013-08-05
DOI:
EISSN:
1521-3773
ISSN:
1433-7851
URN:
uuid:ad87ee41-a0df-45a4-8998-acff85e77389
Source identifiers:
414445
Local pid:
pubs:414445

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