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Independent segregation of the two arms of the Escherichia coli ori region requires neither RNA synthesis nor MreB dynamics.

Abstract:

The mechanism of Escherichia coli chromosome segregation remains elusive. We present results on the simultaneous tracking of segregation of multiple loci in the ori region of the chromosome in cells growing under conditions in which a single round of replication is initiated and completed in the same generation. Loci segregated as expected for progressive replication-segregation from oriC, with markers placed symmetrically on either side of oriC segregating to opposite cell halves at the same...

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Publication status:
Published

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Publisher copy:
10.1128/jb.00861-10

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
Journal of bacteriology
Volume:
192
Issue:
23
Pages:
6143-6153
Publication date:
2010-12-05
DOI:
EISSN:
1098-5530
ISSN:
0021-9193
URN:
uuid:ad731181-6175-4d47-8ad9-ced35a8ca577
Source identifiers:
99750
Local pid:
pubs:99750

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