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Selection and co-selection of antibiotic resistances among Escherichia coli by antibiotic use in primary care: an ecological analysis

Abstract:
Background The majority of studies that link antibiotic usage and resistance focus on simple associations between the resistance against a specific antibiotic and the use of that specific antibiotic. However, the relationship between antibiotic use and resistance is more complex. Here we evaluate selection and co-selection by assessing which antibiotics, including those mainly prescribed for respiratory tract infections, are associated with increased resistance to various ant... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1371/journal.pone.0218134

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Population Health
Role:
Author
ORCID:
0000-0001-7097-8950
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Role:
Author
ORCID:
0000-0002-8874-480X
More by this author
Role:
Author
ORCID:
0000-0001-5179-5702
Publisher:
Public Library of Science Publisher's website
Journal:
PLOS ONE Journal website
Volume:
14
Issue:
6
Pages:
e0218134
DOI:
EISSN:
1932-6203
Pubs id:
pubs:1012634
URN:
uri:ad551ab4-7c7a-4077-938d-025ab372933b
UUID:
uuid:ad551ab4-7c7a-4077-938d-025ab372933b
Local pid:
pubs:1012634
Language:
English

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