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Journal article

Genetic variation in the dopamine D4 receptor (DRD4) gene and smoking cessation: follow-up of a randomised clinical trial of transdermal nicotine patch.

Abstract:

Smokers of European ancestry (n=720) who participated in a double-blind, randomised, placebo-controlled trial of transdermal nicotine replacement therapy, were genotyped for two functional polymorphisms (variable number of tandem repeats (VNTR) and a C to T transition at position -521 (C-521T)) in the dopamine D4 receptor gene (DRD4) gene. Logistic regression models of abstinence at 12- and 26-week follow-ups were carried out separately for each polymorphism. For the DRD4 VNTR models, the mai...

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Publication status:
Published

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Publisher copy:
10.1038/sj.tpj.6500447

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
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Journal:
The pharmacogenomics journal
Volume:
8
Issue:
2
Pages:
122-128
Publication date:
2008-04-05
DOI:
EISSN:
1473-1150
ISSN:
1470-269X
URN:
uuid:ad45e016-e794-4a37-94b7-254940ace256
Source identifiers:
191153
Local pid:
pubs:191153

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