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Journal article

Biological gene delivery vehicles: beyond viral vectors.

Abstract:

Gene therapy covers a broad spectrum of applications, from gene replacement and knockdown for genetic or acquired diseases such as cancer, to vaccination, each with different requirements for gene delivery. Viral vectors and synthetic liposomes have emerged as the vehicles of choice for many applications today, but both have limitations and risks, including complexity of production, limited packaging capacity, and unfavorable immunological features, which restrict gene therapy applications an...

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Publication status:
Published

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Publisher copy:
10.1038/mt.2009.41

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Molecular therapy : the journal of the American Society of Gene Therapy More from this journal
Volume:
17
Issue:
5
Pages:
767-777
Publication date:
2009-05-01
DOI:
EISSN:
1525-0024
ISSN:
1525-0016
Language:
English
Keywords:
Pubs id:
pubs:113308
UUID:
uuid:ad4357b9-97e5-43b1-ba42-6d85e0d61b22
Local pid:
pubs:113308
Source identifiers:
113308
Deposit date:
2012-12-19

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