Journal article icon

Journal article

Disentangling juxtacrine from paracrine signalling in dynamic tissue

Abstract:

Prolactin is a major hormone product of the pituitary gland, the central endocrine regulator. Despite its physiological importance, the cell-level mechanisms of prolactin production are not well understood. Having significantly improved the resolution of real-time-single-cell-GFP-imaging, the authors recently revealed that prolactin gene transcription is highly dynamic and stochastic yet shows space-time coordination in an intact tissue slice. However, it still remains an open question as to ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pcbi.1007030

Authors


More by this author
Role:
Author
ORCID:
0000-0003-0033-1136
Publisher:
Public Library of Science
Journal:
PLOS Computational Biology More from this journal
Volume:
15
Issue:
6
Article number:
e1007030
Publication date:
2019-06-13
Acceptance date:
2019-04-15
DOI:
EISSN:
1553-7358
ISSN:
1553-734X
Pmid:
31194728
Language:
English
Keywords:
Pubs id:
pubs:1014162
UUID:
uuid:ad41983f-7ac0-4627-8009-eaf18f6159c9
Local pid:
pubs:1014162
Source identifiers:
1014162
Deposit date:
2019-07-04

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP