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Journal article

High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes.

Abstract:

AIMS: To measure the activity of the key phosphotransfer enzymes creatine kinase (CK), adenylate kinase (AK), and glycolytic enzymes in two common mouse models of chronic heart failure. METHODS AND RESULTS: C57BL/6 mice were subjected to transverse aortic constriction (TAC), myocardial infarction induced by coronary artery ligation (CAL), or sham operation. Activities of phosphotransfer enzymes CK, AK, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 3-phosphoglycerate kinase (PGK), and pyru...

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Publication status:
Published

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Publisher copy:
10.1093/eurjhf/hfq174

Authors


Aksentijević, D More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Makinen, K More by this author
Sebag-Montefiore, L More by this author
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Journal:
European journal of heart failure
Volume:
12
Issue:
12
Pages:
1282-1289
Publication date:
2010-12-05
DOI:
EISSN:
1879-0844
ISSN:
1388-9842
URN:
uuid:ad3f935f-6765-4914-9a9c-b3057eeba06e
Source identifiers:
105322
Local pid:
pubs:105322

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