Journal article icon

Journal article

Impact of schedule duration on head and neck radiotherapy: Accelerated tumor repopulation versus compensatory mucosal proliferation

Abstract:

Purpose: To determine how modelled maximum tumor control rates, achievable without exceeding mucositis tolerance (tcp max-early) vary with schedule duration for head and neck squamous cell carcinoma (HNSCC). Methods and materials: Using maximum-likelihood techniques, we have fitted a range of tcp models to two HNSCC datasets (Withers' and British Institute of Radiology [BIR]), characterizing the dependence of tcp on duration and equivalent dose in 2 Gy fractions (EQD 2). Models likely to best...

Expand abstract

Actions


Access Document


Authors


Journal:
International Journal of Radiation Oncology Biology Physics
Volume:
82
Issue:
2
Pages:
1021-1030
Publication date:
2012-02-01
DOI:
EISSN:
1879-355X
ISSN:
0360-3016
Source identifiers:
254423
Language:
English
Keywords:
Pubs id:
pubs:254423
UUID:
uuid:ad3dff3a-b208-4548-b4d1-9c10ddeac83f
Local pid:
pubs:254423
Deposit date:
2013-11-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP