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Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT)

Abstract:
Background
The Helicobacter Eradication Aspirin Trial (HEAT) is a multicentre, double blind, randomised controlled trial investigating whether Helicobacter (H.) pylori eradication reduces hospitalisation for peptic ulcer bleeding. Recruited participants were aged 60 and over and taking aspirin (≤325 mg daily) for at least four months prior to consent. Based on results of a pilot study, a sample size calculation predicted 6600 H. pylori-positive randomised participants wou... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-022-06054-w

Authors


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Role:
Author
ORCID:
0000-0003-3533-1005
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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0001-7976-7172
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National Institute for Health Research Health Technology Assessment programme More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
23
Article number:
140
Publication date:
2022-02-14
Acceptance date:
2022-01-27
DOI:
EISSN:
1745-6215
Pmid:
35164864
Language:
English
Keywords:
Pubs id:
1240245
Local pid:
pubs:1240245
Deposit date:
2022-03-11

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