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Journal article

Survivin as a biological biomarker for diagnosis and therapy

Abstract:

Introduction: Survivin (SVN) is a member of the inhibitor of apoptosis (IAP) protein family that promotes cellular proliferation and inhibits apoptosis. Overexpression of SVN is associated with autoimmune disease, hyperplasia, and tumors and can be used as a biomarker in these diseases. SVN is widely recognized as a tumor-associated antigen (TAA) and has become an important target for cancer diagnosis and treatment.
Areas covered: We reviewed SVN res... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/14712598.2021.1918672

Authors


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Institution:
University of Oxford
Division:
MSD
Sub department:
Oncology
Role:
Author
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Name:
Mary Kinross Charitable Trust
Publisher:
Taylor and Francis
Journal:
Expert Opinion on Biological Therapy More from this journal
Volume:
21
Issue:
11
Pages:
1429-1441
Publication date:
2021-06-21
Acceptance date:
2021-04-14
DOI:
EISSN:
1744-7682
ISSN:
1471-2598
Pmid:
33877952
Language:
English
Keywords:
Pubs id:
1172757
Local pid:
pubs:1172757
Deposit date:
2021-07-14

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