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Methodological Issues Surrounding the Use of Baseline Health-Related Quality of Life Data to Inform Trial-Based Economic Evaluations of Interventions Within Emergency and Critical Care Settings: A Systematic Literature Review

Abstract:

Background: Trial-based cost-utility analyses require health-related quality of life data that generate utility values in order to express health outcomes in terms of quality-adjusted life years (QALYs). Assessments of baseline health-related quality of life are problematic where trial participants are incapacitated or critically ill at the time of randomisation. This review aims to identify and critique methods for handling non-availability of baseline health-related quality of life data ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s40273-016-0485-x

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Springer Verlag & Adis
Journal:
PharmacoEconomics More from this journal
Volume:
35
Issue:
5
Pages:
501-515
Publication date:
2017-01-06
Acceptance date:
2017-01-06
DOI:
EISSN:
1179-2027
ISSN:
1170-7690
Keywords:
Pubs id:
pubs:668689
UUID:
uuid:ad1c2de0-40d8-43d0-87c5-5f72bd3f429d
Local pid:
pubs:668689
Source identifiers:
668689
Deposit date:
2017-01-09

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