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Journal article

Region-specific effects of a tyrosine-free amino acid mixture on amphetamine-induced changes in BOLD fMRI signal in the rat brain.

Abstract:

BACKGROUND: Acute depletion of tyrosine using a tyrosine-free amino acid mixture offers a novel dietary approach to inhibit activated dopamine pathways in the brain. This study investigated the potential of in vivo functional magnetic resonance imaging (fMRI) methods as a noninvasive means to detect effects of tyrosine depletion on dopamine function. METHODS: Changes in blood-oxgenation level dependent (BOLD) contrast induced by administration of the dopamine-releasing agent, amphetamine (3 ...

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Publication status:
Published

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Publisher copy:
10.1002/syn.20442

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Journal:
Synapse (New York, N.Y.) More from this journal
Volume:
61
Issue:
11
Pages:
925-932
Publication date:
2007-11-01
DOI:
EISSN:
1098-2396
ISSN:
0887-4476
Language:
English
Keywords:
Pubs id:
pubs:131135
UUID:
uuid:ad0b8a5c-4884-4bfb-9600-d1a0977ef0de
Local pid:
pubs:131135
Source identifiers:
131135
Deposit date:
2012-12-19

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