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Journal article

Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer.

Abstract:

BACKGROUND: The type 1 insulin-like growth factor receptor (IGF1R) plays a critical role in transformation, invasion and apoptosis protection, and is an attractive cancer treatment target. OBJECTIVE: To review IGF1R antibodies and kinase inhibitors that are in preclinical and clinical development, and to discuss questions that will influence the success of this approach in clinical practice. METHODS: This review is drawn from published literature, meeting abstracts and online resources. RESUL...

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Publication status:
Published

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Publisher copy:
10.1517/14728222.12.5.589

Authors


Journal:
Expert opinion on therapeutic targets
Volume:
12
Issue:
5
Pages:
589-603
Publication date:
2008-05-01
DOI:
EISSN:
1744-7631
ISSN:
1472-8222
Source identifiers:
178667
Language:
English
Keywords:
Pubs id:
pubs:178667
UUID:
uuid:ad02e873-e188-45cc-86a2-52018c45d5d4
Local pid:
pubs:178667
Deposit date:
2012-12-19

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