Journal article
Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritis.
- Abstract:
-
Cytosolic phospholipase A2alpha (cPLA2) plays an important role in the development of several inflammatory diseases. The aim of the present study is to determine whether inhibition of cPLA2 expression, using specific antisense oligonucleotides against cPLA2 (antisense), is efficient in reducing inflammation after its development. Two mouse models of inflammation were included in the study: thioglicolate peritonitis and collagen-induced arthritis (CIA). The antisense was found to be specific a...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/eji.200838545
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Authors
Bibliographic Details
- Journal:
- European journal of immunology
- Volume:
- 38
- Issue:
- 10
- Pages:
- 2905-2915
- Publication date:
- 2008-10-01
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- Source identifiers:
-
223910
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:223910
- UUID:
-
uuid:acf19bf1-158d-4d06-9f78-8fdd1e96696f
- Local pid:
- pubs:223910
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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